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Brivanib in combination with Notch3 silencing shows potent activity in tumour models

Brivanib in combination with Notch3 silencing shows potent activity in tumour models

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6461893

Brivanib in combination with Notch3 silencing shows potent activity in tumour models

About this item

Full title

Brivanib in combination with Notch3 silencing shows potent activity in tumour models

Publisher

London: Nature Publishing Group UK

Journal title

British journal of cancer, 2019-03, Vol.120 (6), p.601-611

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Background
Sorafenib is the first targeted agent proven to improve survival of patients with advanced hepatocellular carcinoma (HCC) and it has been used in first line treatments with heterogeneous response across patients. Most of the promising agents evaluated in first-line or second-line phase III trials for HCC failed to improve patient surv...

Alternative Titles

Full title

Brivanib in combination with Notch3 silencing shows potent activity in tumour models

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6461893

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6461893

Other Identifiers

ISSN

0007-0920

E-ISSN

1532-1827

DOI

10.1038/s41416-018-0375-4

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