Differential effects, on oncogenic pathway signalling, by derivatives of the HNF4 α inhibitor BI6015
Differential effects, on oncogenic pathway signalling, by derivatives of the HNF4 α inhibitor BI6015
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Background
Gastric cancer (GC) is a highly heterogeneous disease with few “targeted” therapeutic options. Previously, we demonstrated involvement of the transcription factor HNF4α in human GC tumours, and the developmental signal mediator, WNT5A, as a prognostic GC biomarker. One previously developed HNF4α antagonist, BI6015, while not advancing...
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Full title
Differential effects, on oncogenic pathway signalling, by derivatives of the HNF4 α inhibitor BI6015
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6461897
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6461897
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ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/s41416-018-0374-5
