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Inhibition of the lncRNA SAF drives activation of apoptotic effector caspases in HIV-1–infected huma...

Inhibition of the lncRNA SAF drives activation of apoptotic effector caspases in HIV-1–infected huma...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6462110

Inhibition of the lncRNA SAF drives activation of apoptotic effector caspases in HIV-1–infected human macrophages

About this item

Full title

Inhibition of the lncRNA SAF drives activation of apoptotic effector caspases in HIV-1–infected human macrophages

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2019-04, Vol.116 (15), p.7431-7438

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Long noncoding RNAs (lncRNAs) impart significant regulatory functions in a diverse array of biological pathways and manipulation of these RNAs provides an important avenue to modulate such pathways, particularly in disease. Our knowledge about lncRNAs’ role in determination of cellular fate during HIV-1 infection remains sparse. Here, we have ident...

Alternative Titles

Full title

Inhibition of the lncRNA SAF drives activation of apoptotic effector caspases in HIV-1–infected human macrophages

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6462110

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6462110

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1818662116

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