A new class of synthetic retinoid antibiotics effective against bacterial persisters
A new class of synthetic retinoid antibiotics effective against bacterial persisters
About this item
Full title
Author / Creator
Kim, Wooseong , Zhu, Wenpeng , Hendricks, Gabriel Lambert , Van Tyne, Daria , Steele, Andrew D. , Keohane, Colleen E. , Fricke, Nico , Conery, Annie L. , Shen, Steven , Pan, Wen , Lee, Kiho , Rajamuthiah, Rajmohan , Fuchs, Beth Burgwyn , Vlahovska, Petia M. , Wuest, William M. , Gilmore, Michael S. , Gao, Huajian , Ausubel, Frederick M. and Mylonakis, Eleftherios
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Synthetic retinoid compounds can kill both growing and persister MRSA cells by disrupting the membrane lipid bilayer, and are effective in a mouse model of chronic MRSA infection.
Drugs to beat persistence
Bacterial persisters are a subpopulation of cells that can survive lethal antibiotics and other stresses. They are a major challenge for a...
Alternative Titles
Full title
A new class of synthetic retinoid antibiotics effective against bacterial persisters
Authors, Artists and Contributors
Author / Creator
Zhu, Wenpeng
Hendricks, Gabriel Lambert
Van Tyne, Daria
Steele, Andrew D.
Keohane, Colleen E.
Fricke, Nico
Conery, Annie L.
Shen, Steven
Pan, Wen
Lee, Kiho
Rajamuthiah, Rajmohan
Fuchs, Beth Burgwyn
Vlahovska, Petia M.
Wuest, William M.
Gilmore, Michael S.
Gao, Huajian
Ausubel, Frederick M.
Mylonakis, Eleftherios
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6462414
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6462414
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature26157
