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Metabolic regulation of transcription through compartmentalized NAD + biosynthesis

Metabolic regulation of transcription through compartmentalized NAD + biosynthesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6465534

Metabolic regulation of transcription through compartmentalized NAD + biosynthesis

About this item

Full title

Metabolic regulation of transcription through compartmentalized NAD + biosynthesis

Publisher

United States: The American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2018-05, Vol.360 (6389)

Language

English

Formats

Publication information

Publisher

United States: The American Association for the Advancement of Science

More information

Scope and Contents

Contents

Consuming too much glucose makes you fat, but it is unclear how this conversion is mediated by the body. Glycolysis links to gene transcription via the essential coenzyme nicotinamide adenine dinucleotide in its oxidized state (NAD
+
). Ryu
et al.
found that compartmentalized NAD
+
synthesis and consumption integrate glucose metab...

Alternative Titles

Full title

Metabolic regulation of transcription through compartmentalized NAD + biosynthesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6465534

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6465534

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.aan5780

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