Metabolic regulation of transcription through compartmentalized NAD + biosynthesis
Metabolic regulation of transcription through compartmentalized NAD + biosynthesis
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Publisher
United States: The American Association for the Advancement of Science
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Language
English
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United States: The American Association for the Advancement of Science
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Contents
NAD
(nicotinamide adenine dinucleotide in its oxidized state) is an essential molecule for a variety of physiological processes. It is synthesized in distinct subcellular compartments by three different synthases (NMNAT-1, -2, and -3). We found that compartmentalized NAD
synthesis by NMNATs integrates glucose metabolism and adipogenic transcr...
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Full title
Metabolic regulation of transcription through compartmentalized NAD + biosynthesis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6465534
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6465534
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aan5780