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Detection and Differentiation of Breast Cancer Sub-Types using a cPLA2α Activatable Fluorophore

Detection and Differentiation of Breast Cancer Sub-Types using a cPLA2α Activatable Fluorophore

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6467920

Detection and Differentiation of Breast Cancer Sub-Types using a cPLA2α Activatable Fluorophore

About this item

Full title

Detection and Differentiation of Breast Cancer Sub-Types using a cPLA2α Activatable Fluorophore

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2019-04, Vol.9 (1), p.6122-6122, Article 6122

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Cytosolic phospholipase A2α (cPLA2α) has been shown to be elevated in breast cancer and is a potential biomarker in the differentiation of molecular sub-types. Using a cPLA2α activatable fluorophore, DDAO arachidonate, we explore its ability to function as a contrast agent in fluorescence-guided surgery. In cell lines ranging in cPLA2α expression a...

Alternative Titles

Full title

Detection and Differentiation of Breast Cancer Sub-Types using a cPLA2α Activatable Fluorophore

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6467920

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6467920

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-019-41626-y

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