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Killing Mechanisms of Chimeric Antigen Receptor (CAR) T Cells

Killing Mechanisms of Chimeric Antigen Receptor (CAR) T Cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6470706

Killing Mechanisms of Chimeric Antigen Receptor (CAR) T Cells

About this item

Full title

Killing Mechanisms of Chimeric Antigen Receptor (CAR) T Cells

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2019-03, Vol.20 (6), p.1283

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Effective adoptive T cell therapy (ACT) comprises the killing of cancer cells through the therapeutic use of transferred T cells. One of the main ACT approaches is chimeric antigen receptor (CAR) T cell therapy. CAR T cells mediate MHC-unrestricted tumor cell killing by enabling T cells to bind target cell surface antigens through a single-chain va...

Alternative Titles

Full title

Killing Mechanisms of Chimeric Antigen Receptor (CAR) T Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6470706

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6470706

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms20061283

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