Killing Mechanisms of Chimeric Antigen Receptor (CAR) T Cells
Killing Mechanisms of Chimeric Antigen Receptor (CAR) T Cells
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Effective adoptive T cell therapy (ACT) comprises the killing of cancer cells through the therapeutic use of transferred T cells. One of the main ACT approaches is chimeric antigen receptor (CAR) T cell therapy. CAR T cells mediate MHC-unrestricted tumor cell killing by enabling T cells to bind target cell surface antigens through a single-chain va...
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Full title
Killing Mechanisms of Chimeric Antigen Receptor (CAR) T Cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6470706
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6470706
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms20061283