Phospholipid membranes drive abdominal aortic aneurysm development through stimulating coagulation f...
Phospholipid membranes drive abdominal aortic aneurysm development through stimulating coagulation factor activity
About this item
Full title
Author / Creator
Allen-Redpath, Keith , Aldrovandi, Maceler , Lauder, Sarah N. , Gketsopoulou, Anastasia , Tyrrell, Victoria J. , Slatter, David A. , Andrews, Robert , Watkins, W. John , Atkinson, Georgia , McNeill, Eileen , Gilfedder, Anna , Protty, Majd , Burston, James , Johnson, Sam R. C. , Rodrigues, Patricia R. S. , Jones, Dylan O. , Lee, Regent , Handa, Ashok , Channon, Keith , Obaji, Samya , Alvarez-Jarreta, Jorge , Krönke, Gerhard , Ackermann, Jochen , Jenkins, P. Vince , Collins, Peter W. and O’Donnell, Valerie B.
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Abdominal aortic aneurysm (AAA) is an inflammatory vascular disease with high mortality and limited treatment options. How blood lipids regulate AAA development is unknown. Here lipidomics and genetic models demonstrate a central role for procoagulant enzymatically oxidized phospholipids (eoxPL) in regulating AAA. Specifically, through activating c...
Alternative Titles
Full title
Phospholipid membranes drive abdominal aortic aneurysm development through stimulating coagulation factor activity
Authors, Artists and Contributors
Author / Creator
Aldrovandi, Maceler
Lauder, Sarah N.
Gketsopoulou, Anastasia
Tyrrell, Victoria J.
Slatter, David A.
Andrews, Robert
Watkins, W. John
Atkinson, Georgia
McNeill, Eileen
Gilfedder, Anna
Protty, Majd
Burston, James
Johnson, Sam R. C.
Rodrigues, Patricia R. S.
Jones, Dylan O.
Lee, Regent
Handa, Ashok
Channon, Keith
Obaji, Samya
Alvarez-Jarreta, Jorge
Krönke, Gerhard
Ackermann, Jochen
Jenkins, P. Vince
Collins, Peter W.
O’Donnell, Valerie B.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6475397
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6475397
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1814409116
