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The STEP61 interactome reveals subunit-specific AMPA receptor binding and synaptic regulation

The STEP61 interactome reveals subunit-specific AMPA receptor binding and synaptic regulation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6475416

The STEP61 interactome reveals subunit-specific AMPA receptor binding and synaptic regulation

About this item

Full title

The STEP61 interactome reveals subunit-specific AMPA receptor binding and synaptic regulation

Publisher

Washington: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2019-04, Vol.116 (16), p.8028-8037

Language

English

Formats

Publication information

Publisher

Washington: National Academy of Sciences

More information

Scope and Contents

Contents

Striatal-enriched protein tyrosine phosphatase (STEP) is a brain-specific protein phosphatase that regulates a variety of synaptic proteins, including NMDA receptors (NAMDRs). To better understand STEP’s effect on other receptors, we used mass spectrometry to identify the STEP61 interactome. We identified a number of known interactors, but also one...

Alternative Titles

Full title

The STEP61 interactome reveals subunit-specific AMPA receptor binding and synaptic regulation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6475416

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6475416

Other Identifiers

ISSN

0027-8424,1091-6490

E-ISSN

1091-6490

DOI

10.1073/pnas.1900878116

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