De novo assembly of haplotype-resolved genomes with trio binning
De novo assembly of haplotype-resolved genomes with trio binning
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Trio binning assembles both haplotypes of a genome by combining long-read sequence data with short-read data from both parents.
Complex allelic variation hampers the assembly of haplotype-resolved sequences from diploid genomes. We developed trio binning, an approach that simplifies haplotype assembly by resolving allelic variation before assemb...
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Full title
De novo assembly of haplotype-resolved genomes with trio binning
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6476705
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6476705
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ISSN
1087-0156,1546-1696
E-ISSN
1546-1696
DOI
10.1038/nbt.4277
