Pharmacological boost of DNA damage response and repair by enhanced biogenesis of DNA damage respons...
Pharmacological boost of DNA damage response and repair by enhanced biogenesis of DNA damage response RNAs
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Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
A novel class of small non-coding RNAs called DNA damage response RNAs (DDRNAs) generated at DNA double-strand breaks (DSBs) in a DROSHA- and DICER-dependent manner has been shown to regulate the DNA damage response (DDR). Similar molecules were also reported to guide DNA repair. Here, we show that DDR activation and DNA repair can be pharmacologic...
Alternative Titles
Full title
Pharmacological boost of DNA damage response and repair by enhanced biogenesis of DNA damage response RNAs
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6478851
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6478851
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-42892-6
