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The ZZ domain of p300 mediates specificity of the adjacent HAT domain for histone H3

The ZZ domain of p300 mediates specificity of the adjacent HAT domain for histone H3

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6482957

The ZZ domain of p300 mediates specificity of the adjacent HAT domain for histone H3

About this item

Full title

The ZZ domain of p300 mediates specificity of the adjacent HAT domain for histone H3

Publisher

New York: Nature Publishing Group US

Journal title

Nature structural & molecular biology, 2018-09, Vol.25 (9), p.841-849

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Human p300 is a transcriptional co-activator and a major acetyltransferase that acetylates histones and other proteins facilitating gene transcription. The activity of p300 relies on the fine-tuned interactome that involves a dozen p300 domains and hundreds of binding partners and links p300 to a wide range of vital signaling events. Here, we repor...

Alternative Titles

Full title

The ZZ domain of p300 mediates specificity of the adjacent HAT domain for histone H3

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6482957

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6482957

Other Identifiers

ISSN

1545-9993

E-ISSN

1545-9985

DOI

10.1038/s41594-018-0114-9

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