Perioperative systemic therapy and cytoreductive surgery with HIPEC versus upfront cytoreductive sur...
Perioperative systemic therapy and cytoreductive surgery with HIPEC versus upfront cytoreductive surgery with HIPEC alone for isolated resectable colorectal peritoneal metastases: protocol of a multicentre, open-label, parralel-group, phase II-III, randomised, superiority study
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Author / Creator
Rovers, Koen P , Bakkers, Checca , Simkens, Geert A. A. M , Burger, Jacobus W. A , Nienhuijs, Simon W , Creemers, Geert-Jan M , Thijs, Anna M. J , Brandt-Kerkhof, Alexandra R. M , Madsen, Eva V. E , Ayez, Ninos , de Boer, Nadine L , van Meerten, Esther , Tuynman, Jurriaan B , Kusters, Miranda , Sluiter, Nina R , Verheul, Henk M. W , van der Vliet, Hans J , Wiezer, Marinus J , Boerma, Djamila , Wassenaar, Emma C. E , Los, Maartje , Hunting, Cornelis B , Aalbers, Arend G. J , Kok, Niels F. M , Kuhlmann, Koert F. D , Boot, Henk , Chalabi, Myriam , Kruijff, Schelto , Been, Lukas B , van Ginkel, Robert J , de Groot, Derk Jan A , Fehrmann, Rudolf S. N , de Wilt, Johannes H. W , Bremers, Andreas J. A , de Reuver, Philip R , Radema, Sandra A , Herbschleb, Karin H , van Grevenstein, Wilhelmina M. U , Witkamp, Arjen J , Koopman, Miriam , Haj Mohammad, Nadia , van Duyn, Eino B , Mastboom, Walter J. B , Mekenkamp, Leonie J. M , Nederend, Joost , Lahaye, Max J , Snaebjornsson, Petur , Verhoef, Cornelis , van Laarhoven, Hanneke W. M , Zwinderman, Aeilko H , Bouma, Jeanette M , Kranenburg, Onno , van 't Erve, Iris , Fijneman, Remond J. A , Dijkgraaf, Marcel G. W , Hemmer, Patrick H. J , Punt, Cornelis J. A , Tanis, Pieter J , de Hingh, Ignace H. J. T and ,
Publisher
London: BioMed Central Ltd
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Language
English
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Publisher
London: BioMed Central Ltd
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Scope and Contents
Contents
Background Upfront cytoreductive surgery with HIPEC (CRS-HIPEC) is the standard treatment for isolated resectable colorectal peritoneal metastases (PM) in the Netherlands. This study investigates whether addition of perioperative systemic therapy to CRS-HIPEC improves oncological outcomes. Methods This open-label, parallel-group, phase II-III, rand...
Alternative Titles
Full title
Perioperative systemic therapy and cytoreductive surgery with HIPEC versus upfront cytoreductive surgery with HIPEC alone for isolated resectable colorectal peritoneal metastases: protocol of a multicentre, open-label, parralel-group, phase II-III, randomised, superiority study
Authors, Artists and Contributors
Author / Creator
Bakkers, Checca
Simkens, Geert A. A. M
Burger, Jacobus W. A
Nienhuijs, Simon W
Creemers, Geert-Jan M
Thijs, Anna M. J
Brandt-Kerkhof, Alexandra R. M
Madsen, Eva V. E
Ayez, Ninos
de Boer, Nadine L
van Meerten, Esther
Tuynman, Jurriaan B
Kusters, Miranda
Sluiter, Nina R
Verheul, Henk M. W
van der Vliet, Hans J
Wiezer, Marinus J
Boerma, Djamila
Wassenaar, Emma C. E
Los, Maartje
Hunting, Cornelis B
Aalbers, Arend G. J
Kok, Niels F. M
Kuhlmann, Koert F. D
Boot, Henk
Chalabi, Myriam
Kruijff, Schelto
Been, Lukas B
van Ginkel, Robert J
de Groot, Derk Jan A
Fehrmann, Rudolf S. N
de Wilt, Johannes H. W
Bremers, Andreas J. A
de Reuver, Philip R
Radema, Sandra A
Herbschleb, Karin H
van Grevenstein, Wilhelmina M. U
Witkamp, Arjen J
Koopman, Miriam
Haj Mohammad, Nadia
van Duyn, Eino B
Mastboom, Walter J. B
Mekenkamp, Leonie J. M
Nederend, Joost
Lahaye, Max J
Snaebjornsson, Petur
Verhoef, Cornelis
van Laarhoven, Hanneke W. M
Zwinderman, Aeilko H
Bouma, Jeanette M
Kranenburg, Onno
van 't Erve, Iris
Fijneman, Remond J. A
Dijkgraaf, Marcel G. W
Hemmer, Patrick H. J
Punt, Cornelis J. A
Tanis, Pieter J
de Hingh, Ignace H. J. T
,
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6485075
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6485075
Other Identifiers
ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-019-5545-0
