Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mit...
Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Faithful chromosome segregation depends on the ability of sister kinetochores to attach to spindle microtubules. The outer layer of kinetochores transiently expands in early mitosis to form a fibrous corona, and compacts following microtubule capture. Here we show that the dynein adaptor Spindly and the RZZ (ROD–Zwilch–ZW10) complex drive kinetocho...
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Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6485389
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6485389
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ISSN
1465-7392,1476-4679
E-ISSN
1476-4679
DOI
10.1038/s41556-018-0130-3
