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Potential Applications of NRF2 Inhibitors in Cancer Therapy

Potential Applications of NRF2 Inhibitors in Cancer Therapy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6487091

Potential Applications of NRF2 Inhibitors in Cancer Therapy

About this item

Full title

Potential Applications of NRF2 Inhibitors in Cancer Therapy

Publisher

Cairo, Egypt: Hindawi Publishing Corporation

Journal title

Oxidative medicine and cellular longevity, 2019-01, Vol.2019 (2019), p.1-34

Language

English

Formats

Publication information

Publisher

Cairo, Egypt: Hindawi Publishing Corporation

More information

Scope and Contents

Contents

The NRF2/KEAP1 pathway represents one of the most important cell defense mechanisms against exogenous or endogenous stressors. Indeed, by increasing the expression of several cytoprotective genes, the transcription factor NRF2 can shelter cells and tissues from multiple sources of damage including xenobiotic, electrophilic, metabolic, and oxidative...

Alternative Titles

Full title

Potential Applications of NRF2 Inhibitors in Cancer Therapy

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6487091

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6487091

Other Identifiers

ISSN

1942-0900

E-ISSN

1942-0994

DOI

10.1155/2019/8592348

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