APOBEC-induced mutations and their cancer effect size in head and neck squamous cell carcinoma
APOBEC-induced mutations and their cancer effect size in head and neck squamous cell carcinoma
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Recent studies have revealed the mutational signatures underlying the somatic evolution of cancer, and the prevalences of associated somatic genetic variants. Here we estimate the intensity of positive selection that drives mutations to high frequency in tumors, yielding higher prevalences than expected on the basis of mutation and neutral drift al...
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Full title
APOBEC-induced mutations and their cancer effect size in head and neck squamous cell carcinoma
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6499643
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6499643
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-018-0657-6
