Identification of regulatory variants associated with genetic susceptibility to meningococcal diseas...
Identification of regulatory variants associated with genetic susceptibility to meningococcal disease
About this item
Full title
Author / Creator
EUCLIDS consortium , Borghini, Lisa , Png, Eileen , Binder, Alexander , Wright, Victoria J. , Pinnock, Ellie , de Groot, Ronald , Hazelzet, Jan , Emonts, Marieke , Van der Flier, Michiel , Schlapbach, Luregn J. , Anderson, Suzanne , Secka, Fatou , Salas, Antonio , Fink, Colin , Carrol, Enitan D. , Pollard, Andrew J. , Coin, Lachlan J. , Kuijpers, Taco W. , Martinon-Torres, Federico , Zenz, Werner , Levin, Michael , Hibberd, Martin L. and Davila, Sonia
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Non-coding genetic variants play an important role in driving susceptibility to complex diseases but their characterization remains challenging. Here, we employed a novel approach to interrogate the genetic risk of such polymorphisms in a more systematic way by targeting specific regulatory regions relevant for the phenotype studied. We applied thi...
Alternative Titles
Full title
Identification of regulatory variants associated with genetic susceptibility to meningococcal disease
Authors, Artists and Contributors
Author / Creator
Borghini, Lisa
Png, Eileen
Binder, Alexander
Wright, Victoria J.
Pinnock, Ellie
de Groot, Ronald
Hazelzet, Jan
Emonts, Marieke
Van der Flier, Michiel
Schlapbach, Luregn J.
Anderson, Suzanne
Secka, Fatou
Salas, Antonio
Fink, Colin
Carrol, Enitan D.
Pollard, Andrew J.
Coin, Lachlan J.
Kuijpers, Taco W.
Martinon-Torres, Federico
Zenz, Werner
Levin, Michael
Hibberd, Martin L.
Davila, Sonia
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6502852
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6502852
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-43292-6
