Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in...
Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer’s disease mouse models
About this item
Full title
Author / Creator
Cruz Hernández, Jean C. , Bracko, Oliver , Kersbergen, Calvin J. , Muse, Victorine , Haft-Javaherian, Mohammad , Berg, Maxime , Park, Laibaik , Vinarcsik, Lindsay K. , Ivasyk, Iryna , Rivera, Daniel A. , Kang, Yiming , Cortes-Canteli, Marta , Peyrounette, Myriam , Doyeux, Vincent , Smith, Amy , Zhou, Joan , Otte, Gabriel , Beverly, Jeffrey D. , Davenport, Elizabeth , Davit, Yohan , Lin, Charles P. , Strickland, Sidney , Iadecola, Costantino , Lorthois, Sylvie , Nishimura, Nozomi and Schaffer, Chris B.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Cerebral blood flow (CBF) reductions in Alzheimer’s disease patients and related mouse models have been recognized for decades, but the underlying mechanisms and resulting consequences for Alzheimer’s disease pathogenesis remain poorly understood. In APP/PS1 and 5xFAD mice we found that an increased number of cortical capillaries had stalled blood...
Alternative Titles
Full title
Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer’s disease mouse models
Authors, Artists and Contributors
Author / Creator
Bracko, Oliver
Kersbergen, Calvin J.
Muse, Victorine
Haft-Javaherian, Mohammad
Berg, Maxime
Park, Laibaik
Vinarcsik, Lindsay K.
Ivasyk, Iryna
Rivera, Daniel A.
Kang, Yiming
Cortes-Canteli, Marta
Peyrounette, Myriam
Doyeux, Vincent
Smith, Amy
Zhou, Joan
Otte, Gabriel
Beverly, Jeffrey D.
Davenport, Elizabeth
Davit, Yohan
Lin, Charles P.
Strickland, Sidney
Iadecola, Costantino
Lorthois, Sylvie
Nishimura, Nozomi
Schaffer, Chris B.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6508667
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6508667
Other Identifiers
ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/s41593-018-0329-4
