Intrinsic mutant HTT-mediated defects in oligodendroglia cause myelination deficits and behavioral a...
Intrinsic mutant HTT-mediated defects in oligodendroglia cause myelination deficits and behavioral abnormalities in Huntington disease
About this item
Full title
Author / Creator
Bardile, Costanza Ferrari , Garcia-Miralles, Marta , Caron, Nicholas S. , Rayan, Nirmala Arul , Langley, Sarah R. , Harmston, Nathan , Rondelli, Ana Maria , Teo, Roy Tang Yi , Waltl, Sabine , Anderson, Lisa M. , Bae, Han-Gyu , Jung, Sangyong , Williams, Anna , Prabhakar, Shyam , Petretto, Enrico , Hayden, Michael R. and Pouladi, Mahmoud A.
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Whitematter abnormalities are a nearly universal pathological feature of neurodegenerative disorders including Huntington disease (HD). A long-held assumption is that this white matter pathology is simply a secondary outcome of the progressive neuronal loss that manifests with advancing disease. Using a mouse model of HD, here we show that white ma...
Alternative Titles
Full title
Intrinsic mutant HTT-mediated defects in oligodendroglia cause myelination deficits and behavioral abnormalities in Huntington disease
Authors, Artists and Contributors
Author / Creator
Garcia-Miralles, Marta
Caron, Nicholas S.
Rayan, Nirmala Arul
Langley, Sarah R.
Harmston, Nathan
Rondelli, Ana Maria
Teo, Roy Tang Yi
Waltl, Sabine
Anderson, Lisa M.
Bae, Han-Gyu
Jung, Sangyong
Williams, Anna
Prabhakar, Shyam
Petretto, Enrico
Hayden, Michael R.
Pouladi, Mahmoud A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6511031
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6511031
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1818042116
