Controlling hypoxia-inducible factor-2α is critical for maintaining bone homeostasis in mice
Controlling hypoxia-inducible factor-2α is critical for maintaining bone homeostasis in mice
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Publisher
China: Springer Nature B.V
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Language
English
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China: Springer Nature B.V
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Pathological bone loss is caused by an imbalance between bone formation and resorption. The bone microenvironments are hypoxic, and hypoxia-inducible factor (HIF) is known to play notable roles in bone remodeling. However, the relevant functions of HIF-2α are not well understood. Here, we have shown that HIF-2α deficiency in mice enhances bone mass...
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Full title
Controlling hypoxia-inducible factor-2α is critical for maintaining bone homeostasis in mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6513851
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6513851
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ISSN
2095-4700
E-ISSN
2095-6231
DOI
10.1038/s41413-019-0054-y
