The angiotensin‐(1‐7)/Mas receptor axis protects from endothelial cell senescence via klotho and Nrf...
The angiotensin‐(1‐7)/Mas receptor axis protects from endothelial cell senescence via klotho and Nrf2 activation
About this item
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Author / Creator
Romero, Alejandra , San Hipólito‐Luengo, Álvaro , Villalobos, Laura A. , Vallejo, Susana , Valencia, Inés , Michalska, Patrycja , Pajuelo‐Lozano, Natalia , Sánchez‐Pérez, Isabel , León, Rafael , Bartha, José Luis , Sanz, María Jesús , Erusalimsky, Jorge D. , Sánchez‐Ferrer, Carlos F. , Romacho, Tania and Peiró, Concepción
Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
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Publication information
Publisher
England: John Wiley & Sons, Inc
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More information
Scope and Contents
Contents
Endothelial cell senescence is a hallmark of vascular aging that predisposes to vascular disease. We aimed to explore the capacity of the renin–angiotensin system (RAS) heptapeptide angiotensin (Ang)‐(1‐7) to counteract human endothelial cell senescence and to identify intracellular pathways mediating its potential protective action. In human umbil...
Alternative Titles
Full title
The angiotensin‐(1‐7)/Mas receptor axis protects from endothelial cell senescence via klotho and Nrf2 activation
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6516147
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6516147
Other Identifiers
ISSN
1474-9718,1474-9726
E-ISSN
1474-9726
DOI
10.1111/acel.12913
