Tissue Transglutaminase Appears in Monocytes and Macrophages but Not in Lymphocytes in White Matter...
Tissue Transglutaminase Appears in Monocytes and Macrophages but Not in Lymphocytes in White Matter Multiple Sclerosis Lesions
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Publisher
England: Oxford University Press
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Language
English
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Publisher
England: Oxford University Press
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Abstract
Leukocyte infiltration is an important pathological hallmark of multiple sclerosis (MS) and is therefore targeted by current MS therapies. The enzyme tissue transglutaminase (TG2) contributes to monocyte/macrophage migration and is present in MS lesions and could be a potential therapeutic target. We examined the cellular identity of TG...
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Full title
Tissue Transglutaminase Appears in Monocytes and Macrophages but Not in Lymphocytes in White Matter Multiple Sclerosis Lesions
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6524631
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6524631
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ISSN
0022-3069
E-ISSN
1554-6578
DOI
10.1093/jnen/nlz030