Controlling orthogonal ribosome subunit interactions enables evolution of new function
Controlling orthogonal ribosome subunit interactions enables evolution of new function
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Orthogonal ribosomes are unnatural ribosomes that are directed towards orthogonal messenger RNAs in
Escherichia coli
, through an altered version of the 16S ribosomal RNA of the small subunit
1
. Directed evolution of orthogonal ribosomes has provided access to new ribosomal function, and the evolved orthogonal ribosomes have enabled th...
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Full title
Controlling orthogonal ribosome subunit interactions enables evolution of new function
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6525102
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6525102
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-018-0773-z
