A platform for the discovery of new macrolide antibiotics
A platform for the discovery of new macrolide antibiotics
About this item
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Author / Creator
Seiple, Ian B. , Zhang, Ziyang , Jakubec, Pavol , Langlois-Mercier, Audrey , Wright, Peter M. , Hog, Daniel T. , Yabu, Kazuo , Allu, Senkara Rao , Fukuzaki, Takehiro , Carlsen, Peter N. , Kitamura, Yoshiaki , Zhou, Xiang , Condakes, Matthew L. , Szczypiński, Filip T. , Green, William D. and Myers, Andrew G.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
The chemical modification of structurally complex fermentation products, a process known as semisynthesis, has been an important tool in the discovery and manufacture of antibiotics for the treatment of various infectious diseases. However, many of the therapeutics obtained in this way are no longer effective, because bacterial resistance to these...
Alternative Titles
Full title
A platform for the discovery of new macrolide antibiotics
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6526944
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6526944
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature17967