IL-1α promotes liver inflammation and necrosis during blood-stage Plasmodium chabaudi malaria
IL-1α promotes liver inflammation and necrosis during blood-stage Plasmodium chabaudi malaria
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Malaria causes hepatic inflammation and damage, which contribute to disease severity. The pro-inflammatory cytokine interleukin (IL)-1α is released by non-hematopoietic or hematopoietic cells during liver injury. This study established the role of IL-1α in the liver pathology caused by blood-stage
P. chabaudi
malaria. During acute infection,...
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Full title
IL-1α promotes liver inflammation and necrosis during blood-stage Plasmodium chabaudi malaria
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6527574
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6527574
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-44125-2
