Bhlhe40 mediates tissue-specific control of macrophage proliferation in homeostasis and type 2 immun...
Bhlhe40 mediates tissue-specific control of macrophage proliferation in homeostasis and type 2 immunity
About this item
Full title
Author / Creator
Jarjour, Nicholas N. , Schwarzkopf, Elizabeth A. , Bradstreet, Tara R. , Shchukina, Irina , Lin, Chih-Chung , Huang, Stanley Ching-Cheng , Lai, Chin-Wen , Cook, Melissa E. , Taneja, Reshma , Stappenbeck, Thaddeus S. , Randolph, Gwendalyn J. , Artyomov, Maxim N. , Urban, Joseph F. and Edelson, Brian T.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Most tissue-resident macrophage populations develop during embryogenesis, self-renew in the steady state and expand during type 2 immunity. Whether shared mechanisms regulate the proliferation of macrophages in homeostasis and disease is unclear. Here we found that the transcription factor Bhlhe40 was required in a cell-intrinsic manner for the sel...
Alternative Titles
Full title
Bhlhe40 mediates tissue-specific control of macrophage proliferation in homeostasis and type 2 immunity
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6531324
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6531324
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-019-0382-5
