A photo-cleavable surfactant for top-down proteomics
A photo-cleavable surfactant for top-down proteomics
About this item
Full title
A photo-cleavable surfactant for top-down proteomics
Author / Creator
Journal title
Nature methods, 2019-04, Vol.16 (5), p.417-420
Language
English
Formats
More information
Scope and Contents
Contents
We report the identification of a photo-cleavable anionic surfactant, 4-hexylphenylazosulfonate (Azo) that can be rapidly degraded upon UV irradiation, for top-down proteomics. Azo can effectively solubilize proteins with performance comparable to SDS and is mass spectrometry (MS)-compatible. Importantly, Azo-aided top-down proteomics enables the s...
Alternative Titles
Full title
A photo-cleavable surfactant for top-down proteomics
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6532422
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6532422
Other Identifiers
ISSN
1548-7091
E-ISSN
1548-7105
DOI
10.1038/s41592-019-0391-1
How to access this item
Log in as a Library member
