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The mTORC1-autophagy pathway is a target for senescent cell elimination

The mTORC1-autophagy pathway is a target for senescent cell elimination

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6535413

The mTORC1-autophagy pathway is a target for senescent cell elimination

About this item

Full title

The mTORC1-autophagy pathway is a target for senescent cell elimination

Publisher

Dordrecht: Springer Netherlands

Journal title

Biogerontology (Dordrecht), 2019-06, Vol.20 (3), p.331-335

Language

English

Formats

Publication information

Publisher

Dordrecht: Springer Netherlands

More information

Scope and Contents

Contents

Cellular senescence has recently been established as a key driver of organismal ageing. The state of senescence is controlled by extensive rewiring of signalling pathways, at the heart of which lies the mammalian Target of Rapamycin Complex I (mTORC1). Here we discuss recent publications aiming to establish the mechanisms by which mTORC1 drives the...

Alternative Titles

Full title

The mTORC1-autophagy pathway is a target for senescent cell elimination

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6535413

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6535413

Other Identifiers

ISSN

1389-5729

E-ISSN

1573-6768

DOI

10.1007/s10522-019-09802-9

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