The mTORC1-autophagy pathway is a target for senescent cell elimination
The mTORC1-autophagy pathway is a target for senescent cell elimination
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Publisher
Dordrecht: Springer Netherlands
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Language
English
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Publisher
Dordrecht: Springer Netherlands
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Contents
Cellular senescence has recently been established as a key driver of organismal ageing. The state of senescence is controlled by extensive rewiring of signalling pathways, at the heart of which lies the mammalian Target of Rapamycin Complex I (mTORC1). Here we discuss recent publications aiming to establish the mechanisms by which mTORC1 drives the...
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Full title
The mTORC1-autophagy pathway is a target for senescent cell elimination
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6535413
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6535413
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ISSN
1389-5729
E-ISSN
1573-6768
DOI
10.1007/s10522-019-09802-9