The target landscape of clinical kinase drugs
The target landscape of clinical kinase drugs
About this item
Full title
Author / Creator
Klaeger, Susan , Heinzlmeir, Stephanie , Wilhelm, Mathias , Polzer, Harald , Vick, Binje , Koenig, Paul-Albert , Reinecke, Maria , Ruprecht, Benjamin , Petzoldt, Svenja , Meng, Chen , Zecha, Jana , Reiter, Katrin , Qiao, Huichao , Helm, Dominic , Koch, Heiner , Schoof, Melanie , Canevari, Giulia , Casale, Elena , Re Depaolini, Stefania , Feuchtinger, Annette , Wu, Zhixiang , Schmidt, Tobias , Rueckert, Lars , Becker, Wilhelm , Huenges, Jan , Garz, Anne-Kathrin , Gohlke, Bjoern-Oliver , Zolg, Daniel Paul , Kayser, Gian , Vooder, Tonu , Preissner, Robert , Hahne, Hannes , Tõnisson, Neeme , Kramer, Karl , Götze, Katharina , Bassermann, Florian , Schlegl, Judith , Ehrlich, Hans-Christian , Aiche, Stephan , Walch, Axel , Greif, Philipp A. , Schneider, Sabine , Felder, Eduard Rudolf , Ruland, Juergen , Médard, Guillaume , Jeremias, Irmela , Spiekermann, Karsten and Kuster, Bernhard
Publisher
United States: American Association for the Advancement of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Kinase inhibitors are an important class of drugs that block certain enzymes involved in diseases such as cancer and inflammatory disorders. There are hundreds of kinases within the human body, so knowing the kinase “target” of each drug is essential for developing successful treatment strategies. Sometimes clinical trials can fail because drugs bi...
Alternative Titles
Full title
The target landscape of clinical kinase drugs
Authors, Artists and Contributors
Author / Creator
Heinzlmeir, Stephanie
Wilhelm, Mathias
Polzer, Harald
Vick, Binje
Koenig, Paul-Albert
Reinecke, Maria
Ruprecht, Benjamin
Petzoldt, Svenja
Meng, Chen
Zecha, Jana
Reiter, Katrin
Qiao, Huichao
Helm, Dominic
Koch, Heiner
Schoof, Melanie
Canevari, Giulia
Casale, Elena
Re Depaolini, Stefania
Feuchtinger, Annette
Wu, Zhixiang
Schmidt, Tobias
Rueckert, Lars
Becker, Wilhelm
Huenges, Jan
Garz, Anne-Kathrin
Gohlke, Bjoern-Oliver
Zolg, Daniel Paul
Kayser, Gian
Vooder, Tonu
Preissner, Robert
Hahne, Hannes
Tõnisson, Neeme
Kramer, Karl
Götze, Katharina
Bassermann, Florian
Schlegl, Judith
Ehrlich, Hans-Christian
Aiche, Stephan
Walch, Axel
Greif, Philipp A.
Schneider, Sabine
Felder, Eduard Rudolf
Ruland, Juergen
Médard, Guillaume
Jeremias, Irmela
Spiekermann, Karsten
Kuster, Bernhard
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6542668
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6542668
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aan4368
