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Mediator and RNA polymerase II clusters associate in transcription-dependent condensates

Mediator and RNA polymerase II clusters associate in transcription-dependent condensates

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6543815

Mediator and RNA polymerase II clusters associate in transcription-dependent condensates

About this item

Full title

Mediator and RNA polymerase II clusters associate in transcription-dependent condensates

Publisher

United States: The American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2018-07, Vol.361 (6400), p.412-415

Language

English

Formats

Publication information

Publisher

United States: The American Association for the Advancement of Science

More information

Scope and Contents

Contents

Many components of eukaryotic transcription machinery—such as transcription factors and cofactors including BRD4, subunits of the Mediator complex, and RNA polymerase II—contain intrinsically disordered low-complexity domains. Now a conceptual framework connecting the nature and behavior of their interactions to their functions in transcription reg...

Alternative Titles

Full title

Mediator and RNA polymerase II clusters associate in transcription-dependent condensates

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6543815

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6543815

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.aar4199

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