N-acetylcysteine prevents bladder tissue fibrosis in a lipopolysaccharide-induced cystitis rat model
N-acetylcysteine prevents bladder tissue fibrosis in a lipopolysaccharide-induced cystitis rat model
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Therapeutic options for non-Hunner type interstitial cystitis (IC), which is histologically characterized by fibrosis and mast cell infiltration, are limited. We developed a rat model that replicates chronic inflammation and fibrosis and evaluated the therapeutic effect of N-acetylcysteine (NAC), a well-known anti-fibrotic agent, on the model. Intr...
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N-acetylcysteine prevents bladder tissue fibrosis in a lipopolysaccharide-induced cystitis rat model
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6544636
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6544636
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-44631-3