B cell maturation antigen-specific CAR T cells are clinically active in multiple myeloma
B cell maturation antigen-specific CAR T cells are clinically active in multiple myeloma
About this item
Full title
Author / Creator
Cohen, Adam D , Garfall, Alfred L , Stadtmauer, Edward A , Melenhorst, J Joseph , Lacey, Simon F , Lancaster, Eric , Vogl, Dan T , Weiss, Brendan M , Dengel, Karen , Nelson, Annemarie , Plesa, Gabriela , Chen, Fang , Davis, Megan M , Hwang, Wei-Ting , Young, Regina M , Brogdon, Jennifer L , Isaacs, Randi , Pruteanu-Malinici, Iulian , Siegel, Don L , Levine, Bruce L , June, Carl H and Milone, Michael C
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Chimeric antigen receptor (CAR) T cells are a promising therapy for hematologic malignancies. B-cell maturation antigen (BCMA) is a rational target in multiple myeloma (MM).
We conducted a phase I study of autologous T cells lentivirally-transduced with a fully-human, BCMA-specific CAR containing CD3ζ and 4-1BB signaling domains (CART-BCMA), in...
Alternative Titles
Full title
B cell maturation antigen-specific CAR T cells are clinically active in multiple myeloma
Authors, Artists and Contributors
Author / Creator
Garfall, Alfred L
Stadtmauer, Edward A
Melenhorst, J Joseph
Lacey, Simon F
Lancaster, Eric
Vogl, Dan T
Weiss, Brendan M
Dengel, Karen
Nelson, Annemarie
Plesa, Gabriela
Chen, Fang
Davis, Megan M
Hwang, Wei-Ting
Young, Regina M
Brogdon, Jennifer L
Isaacs, Randi
Pruteanu-Malinici, Iulian
Siegel, Don L
Levine, Bruce L
June, Carl H
Milone, Michael C
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6546468
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6546468
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI126397
