B cell maturation antigen–specific CAR T cells are clinically active in multiple myeloma
B cell maturation antigen–specific CAR T cells are clinically active in multiple myeloma
About this item
Full title
Author / Creator
Cohen, Adam D. , Garfall, Alfred L. , Stadtmauer, Edward A. , Melenhorst, J. Joseph , Lacey, Simon F. , Lancaster, Eric , Vogl, Dan T. , Weiss, Brendan M. , Dengel, Karen , Nelson, Annemarie , Plesa, Gabriela , Chen, Fang , Davis, Megan M. , Hwang, Wei-Ting , Young, Regina M. , Brogdon, Jennifer L. , Isaacs, Randi , Pruteanu-Malinici, Iulian , Siegel, Don L. , Levine, Bruce L. , June, Carl H. and Milone, Michael C.
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Chimeric antigen receptor (CAR) T cells are a promising therapy for hematologic malignancies. B-cell maturation antigen (BCMA) is a rational target in multiple myeloma (MM).
We conducted a phase I study of autologous T cells lentivirally-transduced with a fully-human, BCMA-specific CAR containing CD3ζ and 4-1BB signaling domains (CART-BCMA), in...
Alternative Titles
Full title
B cell maturation antigen–specific CAR T cells are clinically active in multiple myeloma
Authors, Artists and Contributors
Author / Creator
Garfall, Alfred L.
Stadtmauer, Edward A.
Melenhorst, J. Joseph
Lacey, Simon F.
Lancaster, Eric
Vogl, Dan T.
Weiss, Brendan M.
Dengel, Karen
Nelson, Annemarie
Plesa, Gabriela
Chen, Fang
Davis, Megan M.
Hwang, Wei-Ting
Young, Regina M.
Brogdon, Jennifer L.
Isaacs, Randi
Pruteanu-Malinici, Iulian
Siegel, Don L.
Levine, Bruce L.
June, Carl H.
Milone, Michael C.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6546468
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6546468
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI126397
