Crossing the Chloride Channel: The Current and Potential Therapeutic Value of the Neuronal K+-Cl- Co...
Crossing the Chloride Channel: The Current and Potential Therapeutic Value of the Neuronal K+-Cl- Cotransporter KCC2
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Publisher
Cairo, Egypt: Hindawi Publishing Corporation
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Language
English
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Cairo, Egypt: Hindawi Publishing Corporation
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Contents
Chloride (Cl-) homeostasis is an essential process involved in neuronal signalling and cell survival. Inadequate regulation of intracellular Cl- interferes with synaptic signalling and is implicated in several neurological diseases. The main inhibitory neurotransmitter of the central nervous system is γ-aminobutyric acid (GABA). GABA hyperpolarises...
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Full title
Crossing the Chloride Channel: The Current and Potential Therapeutic Value of the Neuronal K+-Cl- Cotransporter KCC2
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6556333
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6556333
Other Identifiers
ISSN
2314-6133
E-ISSN
2314-6141
DOI
10.1155/2019/8941046