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Crossing the Chloride Channel: The Current and Potential Therapeutic Value of the Neuronal K+-Cl- Co...

Crossing the Chloride Channel: The Current and Potential Therapeutic Value of the Neuronal K+-Cl- Co...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6556333

Crossing the Chloride Channel: The Current and Potential Therapeutic Value of the Neuronal K+-Cl- Cotransporter KCC2

About this item

Full title

Crossing the Chloride Channel: The Current and Potential Therapeutic Value of the Neuronal K+-Cl- Cotransporter KCC2

Author / Creator

Publisher

Cairo, Egypt: Hindawi Publishing Corporation

Journal title

BioMed research international, 2019-01, Vol.2019 (2019), p.1-12

Language

English

Formats

Publication information

Publisher

Cairo, Egypt: Hindawi Publishing Corporation

More information

Scope and Contents

Contents

Chloride (Cl-) homeostasis is an essential process involved in neuronal signalling and cell survival. Inadequate regulation of intracellular Cl- interferes with synaptic signalling and is implicated in several neurological diseases. The main inhibitory neurotransmitter of the central nervous system is γ-aminobutyric acid (GABA). GABA hyperpolarises...

Alternative Titles

Full title

Crossing the Chloride Channel: The Current and Potential Therapeutic Value of the Neuronal K+-Cl- Cotransporter KCC2

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6556333

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6556333

Other Identifiers

ISSN

2314-6133

E-ISSN

2314-6141

DOI

10.1155/2019/8941046

How to access this item