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Downregulated LRRK2 gene expression inhibits proliferation and migration while promoting the apoptos...

Downregulated LRRK2 gene expression inhibits proliferation and migration while promoting the apoptos...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6561619

Downregulated LRRK2 gene expression inhibits proliferation and migration while promoting the apoptosis of thyroid cancer cells by inhibiting activation of the JNK signaling pathway

About this item

Full title

Downregulated LRRK2 gene expression inhibits proliferation and migration while promoting the apoptosis of thyroid cancer cells by inhibiting activation of the JNK signaling pathway

Publisher

Athens: Spandidos Publications

Journal title

International journal of oncology, 2019-07, Vol.55 (1), p.21-34

Language

English

Formats

Publication information

Publisher

Athens: Spandidos Publications

More information

Scope and Contents

Contents

Emerging studies have indicated that leucine-rich repeat kinase 2 (LRRK2) is associated with thyroid cancer (TC). The present study investigated the effect of LRRK2 on the cell cycle and apoptosis in TC, and examined the underlying mechanisms in vitro. To screen TC-associated differentially expressed genes, gene expression microarray analysis was c...

Alternative Titles

Full title

Downregulated LRRK2 gene expression inhibits proliferation and migration while promoting the apoptosis of thyroid cancer cells by inhibiting activation of the JNK signaling pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6561619

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6561619

Other Identifiers

ISSN

1019-6439

E-ISSN

1791-2423

DOI

10.3892/ijo.2019.4816

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