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Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring

Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6565370

Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring

Publication information

Publisher

London: Nature Publishing Group UK

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis largely owing to inefficient diagnosis and tenacious drug resistance. Activation of pancreatic stellate cells (PSCs) and consequent development of dense stroma are prominent features accounting for this aggressive biology
1
,
2
. The reciprocal interplay between PSCs and pan...

Alternative Titles

Full title

Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6565370

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6565370

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-019-1130-6

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