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Association of germline variants in the APOBEC3 region with cancer risk and enrichment with APOBEC-s...

Association of germline variants in the APOBEC3 region with cancer risk and enrichment with APOBEC-s...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6583788

Association of germline variants in the APOBEC3 region with cancer risk and enrichment with APOBEC-signature mutations in tumors

About this item

Full title

Association of germline variants in the APOBEC3 region with cancer risk and enrichment with APOBEC-signature mutations in tumors

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2016-11, Vol.48 (11), p.1330-1338

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Ludmila Prokunina-Olsson and colleagues report a fine-mapping and association analysis of germline variants in the
APOBEC3
region associated with cancer risk. They identify two variants with differential effects in bladder and breast cancer, and their
in vitro
results suggest that environmental exposures may induce tissue-specific APOBE...

Alternative Titles

Full title

Association of germline variants in the APOBEC3 region with cancer risk and enrichment with APOBEC-signature mutations in tumors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6583788

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6583788

Other Identifiers

ISSN

1061-4036,1546-1718

E-ISSN

1546-1718

DOI

10.1038/ng.3670

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