Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I I...
Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways
About this item
Full title
Author / Creator
Der, Evan , Suryawanshi, Hemant , Morozov, Pavel , Kustagi, Manjunath , Goilav, Beatrice , Ranabothu, Saritha , Izmirly, Peter , Clancy, Robert , Belmont, H. Michael , Koenigsberg, Mordecai , Mokrzycki, Michele , Rominieki, Helen , Graham, Jay A. , Rocca, Juan P. , Bornkamp, Nicole , Jordan, Nicole , Schulte, Emma , Wu, Ming , Pullman, James , Slowikowski, Kamil , Raychaudhuri, Soumya , Guthridge, Joel , James, Judith , Buyon, Jill , Tuschl, Thomas , Putterman, Chaim , the Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Consortium and Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Consortium
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
The molecular and cellular processes that lead to renal damage and to the heterogeneity of lupus nephritis (LN) are not well understood. We applied single-cell RNA sequencing (scRNA-seq) to renal biopsies from patients with LN and evaluated skin biopsies as a potential source of diagnostic and prognostic markers of renal disease. Type I interferon...
Alternative Titles
Full title
Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways
Authors, Artists and Contributors
Author / Creator
Suryawanshi, Hemant
Morozov, Pavel
Kustagi, Manjunath
Goilav, Beatrice
Ranabothu, Saritha
Izmirly, Peter
Clancy, Robert
Belmont, H. Michael
Koenigsberg, Mordecai
Mokrzycki, Michele
Rominieki, Helen
Graham, Jay A.
Rocca, Juan P.
Bornkamp, Nicole
Jordan, Nicole
Schulte, Emma
Wu, Ming
Pullman, James
Slowikowski, Kamil
Raychaudhuri, Soumya
Guthridge, Joel
James, Judith
Buyon, Jill
Tuschl, Thomas
Putterman, Chaim
the Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Consortium
Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Consortium
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6584054
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6584054
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-019-0386-1
