Specific factors in blood from young but not old mice directly promote synapse formation and NMDA-re...
Specific factors in blood from young but not old mice directly promote synapse formation and NMDA-receptor recruitment
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Publisher
United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Scope and Contents
Contents
Aging drives a progressive decline in cognition and decreases synapse numbers and synaptic function in the brain, thereby increasing the risk for neurodegenerative disease. Pioneering studies showed that introduction of blood from young mice into aged mice reversed age-associated cognitive impairments and increased synaptic connectivity in brain, s...
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Full title
Specific factors in blood from young but not old mice directly promote synapse formation and NMDA-receptor recruitment
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6589664
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6589664
Other Identifiers
ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.1902672116
