A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1
A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1
About this item
Full title
Author / Creator
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States) , Zhao, Baoyu , Du, Fenglei , Xu, Pengbiao , Shu, Chang , Sankaran, Banumathi , Bell, Samantha L. , Liu, Mengmeng , Lei, Yuanjiu , Gao, Xinsheng , Fu, Xiaofeng , Zhu, Fanxiu , Liu, Yang , Laganowsky, Arthur , Zheng, Xueyun , Ji, Jun-Yuan , West, A. Phillip , Watson, Robert O. and Li, Pingwei
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Nucleic acids from bacteria or viruses induce potent immune responses in infected cells
1
–
4
. The detection of pathogen-derived nucleic acids is a central strategy by which the host senses infection and initiates protective immune responses
5
,
6
. Cyclic GMP-AMP synthase (cGAS) is a double-stranded DNA sensor
7
,
Alternative Titles
Full title
A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1
Authors, Artists and Contributors
Author / Creator
Zhao, Baoyu
Du, Fenglei
Xu, Pengbiao
Shu, Chang
Sankaran, Banumathi
Bell, Samantha L.
Liu, Mengmeng
Lei, Yuanjiu
Gao, Xinsheng
Fu, Xiaofeng
Zhu, Fanxiu
Liu, Yang
Laganowsky, Arthur
Zheng, Xueyun
Ji, Jun-Yuan
West, A. Phillip
Watson, Robert O.
Li, Pingwei
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6596994
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6596994
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-019-1228-x
