Drp1S600 phosphorylation regulates mitochondrial fission and progression of nephropathy in diabetic...
Drp1S600 phosphorylation regulates mitochondrial fission and progression of nephropathy in diabetic mice
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Publisher
United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Contents
Phosphorylation of Dynamin-related protein1 (Drp1) represents an important regulatory mechanism for mitochondrial fission. Here we established the role of Drp1 Serine 600 (S600) phosphorylation on mitochondrial fission in vivo, and assessed the functional consequences of targeted elimination of the Drp1S600 phosphorylation site in progression of di...
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Full title
Drp1S600 phosphorylation regulates mitochondrial fission and progression of nephropathy in diabetic mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6597204
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6597204
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI127277