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Transcription factor Fra-1 targets arginase-1 to enhance macrophage-mediated inflammation in arthrit...

Transcription factor Fra-1 targets arginase-1 to enhance macrophage-mediated inflammation in arthrit...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6597220

Transcription factor Fra-1 targets arginase-1 to enhance macrophage-mediated inflammation in arthritis

About this item

Full title

Transcription factor Fra-1 targets arginase-1 to enhance macrophage-mediated inflammation in arthritis

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2019-07, Vol.129 (7), p.2669-2684

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

The polarization of macrophages is regulated by transcription factors such as nuclear factor kappa B (NF-κB) and activator protein 1 (AP-1). In this manuscript, we delineated the role of the transcription factor Fos-related antigen 1 (Fra-1) during macrophage activation and development of arthritis. Network level interaction analysis of microarray...

Alternative Titles

Full title

Transcription factor Fra-1 targets arginase-1 to enhance macrophage-mediated inflammation in arthritis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6597220

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6597220

Other Identifiers

ISSN

0021-9738,1558-8238

E-ISSN

1558-8238

DOI

10.1172/JCI96832

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