Transcription factor Fra-1 targets arginase-1 to enhance macrophage-mediated inflammation in arthrit...
Transcription factor Fra-1 targets arginase-1 to enhance macrophage-mediated inflammation in arthritis
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Author / Creator
Hannemann, Nicole , Cao, Shan , Eriksson, Daniel , Schnelzer, Anne , Jordan, Jutta , Eberhardt, Martin , Schleicher, Ulrike , Rech, Jürgen , Ramming, Andreas , Uebe, Steffen , Ekici, Arif , Cañete, Juan D. , Chen, Xiaoxiang , Bäuerle, Tobias , Vera, Julio , Bogdan, Christian , Schett, Georg and Bozec, Aline
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publication information
Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
The polarization of macrophages is regulated by transcription factors such as nuclear factor kappa B (NF-κB) and activator protein 1 (AP-1). In this manuscript, we delineated the role of the transcription factor Fos-related antigen 1 (Fra-1) during macrophage activation and development of arthritis. Network level interaction analysis of microarray...
Alternative Titles
Full title
Transcription factor Fra-1 targets arginase-1 to enhance macrophage-mediated inflammation in arthritis
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6597220
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6597220
Other Identifiers
ISSN
0021-9738,1558-8238
E-ISSN
1558-8238
DOI
10.1172/JCI96832