USP16-mediated deubiquitination of calcineurin A controls peripheral T cell maintenance
USP16-mediated deubiquitination of calcineurin A controls peripheral T cell maintenance
About this item
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Author / Creator
Zhang, Yu , Liu, Rong-bei , Cao, Qian , Fan, Ke-qi , Huang, Ling-jie , Yu, Jian-shuai , Gao, Zheng-jun , Huang, Tao , Zhong, Jiang-yan , Mao, Xin-tao , Wang, Fei , Xiao, Peng , Zhao, Yuan , Feng, Xin-hua , Li, Yi-yuan and Jin, Jin
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publication information
Publisher
United States: American Society for Clinical Investigation
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More information
Scope and Contents
Contents
Calcineurin acts as a calcium-activated phosphatase that dephosphorylates various substrates, including members of the nuclear factor of activated T cells (NFAT) family, to trigger their nuclear translocation and transcriptional activity. However, the detailed mechanism regulating the recruitment of NFATs to calcineurin remains poorly understood. H...
Alternative Titles
Full title
USP16-mediated deubiquitination of calcineurin A controls peripheral T cell maintenance
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6597231
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6597231
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI123801
