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Inhibition of the 60S ribosome biogenesis GTPase LSG1 causes endoplasmic reticular disruption and ce...

Inhibition of the 60S ribosome biogenesis GTPase LSG1 causes endoplasmic reticular disruption and ce...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6612703

Inhibition of the 60S ribosome biogenesis GTPase LSG1 causes endoplasmic reticular disruption and cellular senescence

About this item

Full title

Inhibition of the 60S ribosome biogenesis GTPase LSG1 causes endoplasmic reticular disruption and cellular senescence

Publisher

England: John Wiley & Sons, Inc

Journal title

Aging cell, 2019-08, Vol.18 (4), p.e12981-n/a

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Cellular senescence is triggered by diverse stimuli and is characterized by long‐term growth arrest and secretion of cytokines and chemokines (termed the SASP—senescence‐associated secretory phenotype). Senescence can be organismally beneficial as it can prevent the propagation of damaged or mutated clones and stimulate their clearance by immune ce...

Alternative Titles

Full title

Inhibition of the 60S ribosome biogenesis GTPase LSG1 causes endoplasmic reticular disruption and cellular senescence

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6612703

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6612703

Other Identifiers

ISSN

1474-9718

E-ISSN

1474-9726

DOI

10.1111/acel.12981

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