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Biochemistry, Therapeutics, and Biomarker Implications of Neprilysin in Cardiorenal Disease

Biochemistry, Therapeutics, and Biomarker Implications of Neprilysin in Cardiorenal Disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6613397

Biochemistry, Therapeutics, and Biomarker Implications of Neprilysin in Cardiorenal Disease

About this item

Full title

Biochemistry, Therapeutics, and Biomarker Implications of Neprilysin in Cardiorenal Disease

Publisher

England: Oxford University Press

Journal title

Clinical chemistry (Baltimore, Md.), 2017-01, Vol.63 (1), p.108-115

Language

English

Formats

Publication information

Publisher

England: Oxford University Press

More information

Scope and Contents

Contents

Neprilysin (NEP) is a membrane-bound neutral endopeptidase that degrades a variety of bioactive peptides. The substrates include natriuretic peptides (NPs), which are important regulating mediators for cardiovascular and renal biology. Inhibition of NEP activity and exogenous NP administration thus have emerged as potential therapeutic strategies f...

Alternative Titles

Full title

Biochemistry, Therapeutics, and Biomarker Implications of Neprilysin in Cardiorenal Disease

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6613397

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6613397

Other Identifiers

ISSN

0009-9147

E-ISSN

1530-8561

DOI

10.1373/clinchem.2016.262907

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