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Clustered protocadherins methylation alterations in cancer

Clustered protocadherins methylation alterations in cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6617643

Publication information

Publisher

Germany: BioMed Central

More information

Scope and Contents

Contents

Clustered protocadherins (PCDHs) map in tandem at human chromosome 5q31 and comprise three multi-genes clusters: α-, β- and γ-PCDH. The expression of this cluster consists of a complex mechanism involving DNA hub formation through DNA-CCTC binding factor (CTCF) interaction. Methylation alterations can affect this interaction, leading to transcripti...

Alternative Titles

Full title

Clustered protocadherins methylation alterations in cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6617643

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6617643

Other Identifiers

ISSN

1868-7075,1868-7083

E-ISSN

1868-7083,1868-7075

DOI

10.1186/s13148-019-0695-0

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