The effect of dose on the safety and immunogenicity of the VSV Ebola candidate vaccine: a randomised...
The effect of dose on the safety and immunogenicity of the VSV Ebola candidate vaccine: a randomised double-blind, placebo-controlled phase 1/2 trial
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Author / Creator
VSV-Ebola Consortium , Huttner, Angela, MD , Dayer, Julie-Anne, MD , Yerly, Sabine, MSc , Combescure, Christophe, PhD , Auderset, Floriane, PhD , Desmeules, Jules, Prof , Eickmann, Markus, PhD , Finckh, Axel, Prof , Goncalves, Ana Rita, PhD , Hooper, Jay W, PhD , Kaya, Gürkan, MD , Krähling, Verena, PhD , Kwilas, Steve, PhD , Lemaître, Barbara, MSc , Matthey, Alain, MD , Silvera, Peter, PhD , Becker, Stephan, Prof , Fast, Patricia E, MD , Moorthy, Vasee, MD , Kieny, Marie Paule, PhD , Kaiser, Laurent, Prof and Siegrist, Claire-Anne, Prof
Publisher
United States: Elsevier Ltd
Journal title
Language
English
Formats
Publication information
Publisher
United States: Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
Summary Background Safe and effective vaccines against Ebola could prevent or control outbreaks. The safe use of replication-competent vaccines requires a careful dose-selection process. We report the first safety and immunogenicity results in volunteers receiving 3 × 105 plaque-forming units (pfu) of the recombinant vesicular stomatitis virus-base...
Alternative Titles
Full title
The effect of dose on the safety and immunogenicity of the VSV Ebola candidate vaccine: a randomised double-blind, placebo-controlled phase 1/2 trial
Authors, Artists and Contributors
Author / Creator
Huttner, Angela, MD
Dayer, Julie-Anne, MD
Yerly, Sabine, MSc
Combescure, Christophe, PhD
Auderset, Floriane, PhD
Desmeules, Jules, Prof
Eickmann, Markus, PhD
Finckh, Axel, Prof
Goncalves, Ana Rita, PhD
Hooper, Jay W, PhD
Kaya, Gürkan, MD
Krähling, Verena, PhD
Kwilas, Steve, PhD
Lemaître, Barbara, MSc
Matthey, Alain, MD
Silvera, Peter, PhD
Becker, Stephan, Prof
Fast, Patricia E, MD
Moorthy, Vasee, MD
Kieny, Marie Paule, PhD
Kaiser, Laurent, Prof
Siegrist, Claire-Anne, Prof
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6624136
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6624136
Other Identifiers
ISSN
1473-3099
E-ISSN
1474-4457
DOI
10.1016/S1473-3099(15)00154-1