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Brain histamine H1 receptor occupancy after oral administration of desloratadine and loratadine

Brain histamine H1 receptor occupancy after oral administration of desloratadine and loratadine

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6624455

Brain histamine H1 receptor occupancy after oral administration of desloratadine and loratadine

About this item

Full title

Brain histamine H1 receptor occupancy after oral administration of desloratadine and loratadine

Publisher

Hoboken: John Wiley and Sons Inc

Journal title

Pharmacology research & perspectives, 2019-08, Vol.7 (4), p.n/a

Language

English

Formats

Publication information

Publisher

Hoboken: John Wiley and Sons Inc

More information

Scope and Contents

Contents

Some histamine H1 receptor (H1R) antagonists induce adverse sedative reactions caused by blockade of histamine transmission in the brain. Desloratadine is a second‐generation antihistamine for treatment of allergic disorders. Its binding to brain H1Rs, which is the basis of sedative property of antihistamines, has not been examined previously in th...

Alternative Titles

Full title

Brain histamine H1 receptor occupancy after oral administration of desloratadine and loratadine

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6624455

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6624455

Other Identifiers

ISSN

2052-1707

E-ISSN

2052-1707

DOI

10.1002/prp2.499

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