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Clinical Impact of RANK Signalling in Ovarian Cancer

Clinical Impact of RANK Signalling in Ovarian Cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6627676

Clinical Impact of RANK Signalling in Ovarian Cancer

About this item

Full title

Clinical Impact of RANK Signalling in Ovarian Cancer

Publisher

Switzerland: MDPI AG

Journal title

Cancers, 2019-06, Vol.11 (6), p.791

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Ovarian cancer (OC) is a gynaecological malignancy with poor clinical outcome and limited treatment options. The receptor activator of nuclear factor-κB (RANK) pathway, activated by RANK ligand (RANKL), critically controls bone metabolism, tumourigenesis and tumour immune responses. Denosumab, a monocloncal RANKL antibody, exerts tumour-suppressive...

Alternative Titles

Full title

Clinical Impact of RANK Signalling in Ovarian Cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6627676

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6627676

Other Identifiers

ISSN

2072-6694

E-ISSN

2072-6694

DOI

10.3390/cancers11060791

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