Structure-guided examination of the mechanogating mechanism of PIEZO2
Structure-guided examination of the mechanogating mechanism of PIEZO2
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Piezo channels are mechanically activated ion channels that confer mechanosensitivity to a variety of different cell types. Piezos oligomerize as propeller-shaped homotrimers that are thought to locally curve the membrane into spherical domes that project into the cell. While several studies have identified domains and amino acids that control impo...
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Full title
Structure-guided examination of the mechanogating mechanism of PIEZO2
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6628815
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6628815
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1905985116