Latrophilin GPCRs direct synapse specificity by coincident binding of FLRTs and teneurins
Latrophilin GPCRs direct synapse specificity by coincident binding of FLRTs and teneurins
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United States: American Association for the Advancement of Science
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English
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United States: American Association for the Advancement of Science
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In the brain, synaptic connections are formed with exquisite specificity, but the underlying molecular mechanisms remain largely unexplored. Synapse formation is thought to involve bidirectional signaling by proteins that bind to each other across the synaptic cleft. Sando
et al.
used conditional genetic tools and in vitro assays to investiga...
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Latrophilin GPCRs direct synapse specificity by coincident binding of FLRTs and teneurins
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6636343
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6636343
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ISSN
0036-8075,1095-9203
E-ISSN
1095-9203
DOI
10.1126/science.aav7969
